Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin receptor type B' and Ligand = 'BDBM50290941'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin receptor type B (Sus scrofa)	BDBM50290941 (CHEMBL412865 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-oxo...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(N1N=C(CCC1=O)c1cccs1)c1ccc2OCOc2c1 |c:18| Show InChI InChI=1S/C26H25N3O6S2/c1-16(2)17-5-8-19(9-6-17)37(32,33)28-26(31)25(18-7-11-21-22(14-18)35-15-34-21)29-24(30)12-10-20(27-29)23-4-3-13-36-23/h3-9,11,13-14,16,25H,10,12,15H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of specific binding of [125I]-ET-1 (endothelin 1) to endothelin B receptor of porcine kidney membranes				Bioorg Med Chem Lett 7: 275-280 (1997) Article DOI: 10.1016/S0960-894X(96)00617-8 BindingDB Entry DOI: 10.7270/Q2QF8SWT
					More data for this Ligand-Target Pair