Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50293249'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50293249 (5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...) Show SMILES NC(=O)c1cc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc(c1)C(N)=O Show InChI InChI=1S/C19H15ClN6O4/c20-12-1-2-13-16(30-8-29-13)15(12)25-14-3-4-23-19(26-14)24-11-6-9(17(21)27)5-10(7-11)18(22)28/h1-7H,8H2,(H2,21,27)(H2,22,28)(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4				Bioorg Med Chem Lett 18: 5717-21 (2009) Article DOI: 10.1016/j.bmcl.2008.09.087 BindingDB Entry DOI: 10.7270/Q2N016JJ
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50293249 (5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...) Show SMILES NC(=O)c1cc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc(c1)C(N)=O Show InChI InChI=1S/C19H15ClN6O4/c20-12-1-2-13-16(30-8-29-13)15(12)25-14-3-4-23-19(26-14)24-11-6-9(17(21)27)5-10(7-11)18(22)28/h1-7H,8H2,(H2,21,27)(H2,22,28)(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISA				Bioorg Med Chem Lett 18: 5717-21 (2009) Article DOI: 10.1016/j.bmcl.2008.09.087 BindingDB Entry DOI: 10.7270/Q2N016JJ
					More data for this Ligand-Target Pair