Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50428747'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50428747 (CHEMBL2333600) Show SMILES COc1ccccc1-n1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1ccccc1Cl |(36.42,-49.25,;36.42,-47.71,;37.75,-46.94,;39.09,-47.71,;40.42,-46.94,;40.41,-45.39,;39.08,-44.63,;37.75,-45.4,;36.42,-44.63,;36.43,-43.09,;34.96,-42.61,;34.05,-43.85,;34.95,-45.1,;34.05,-46.35,;32.58,-45.87,;31.25,-46.63,;31.25,-48.17,;29.92,-45.87,;28.59,-46.64,;29.92,-44.33,;31.25,-43.55,;31.25,-42.01,;32.58,-44.33,;37.2,-41.76,;38.74,-41.76,;39.52,-40.43,;38.75,-39.1,;37.2,-39.1,;36.43,-40.43,;34.9,-40.43,)| Show InChI InChI=1S/C21H16ClN5O3/c1-25-18-17(19(28)24-21(25)29)26-11-15(12-7-3-4-8-13(12)22)27(20(26)23-18)14-9-5-6-10-16(14)30-2/h3-11H,1-2H3,(H,24,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assay				J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50428747 (CHEMBL2333600) Show SMILES COc1ccccc1-n1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1ccccc1Cl |(36.42,-49.25,;36.42,-47.71,;37.75,-46.94,;39.09,-47.71,;40.42,-46.94,;40.41,-45.39,;39.08,-44.63,;37.75,-45.4,;36.42,-44.63,;36.43,-43.09,;34.96,-42.61,;34.05,-43.85,;34.95,-45.1,;34.05,-46.35,;32.58,-45.87,;31.25,-46.63,;31.25,-48.17,;29.92,-45.87,;28.59,-46.64,;29.92,-44.33,;31.25,-43.55,;31.25,-42.01,;32.58,-44.33,;37.2,-41.76,;38.74,-41.76,;39.52,-40.43,;38.75,-39.1,;37.2,-39.1,;36.43,-40.43,;34.9,-40.43,)| Show InChI InChI=1S/C21H16ClN5O3/c1-25-18-17(19(28)24-21(25)29)26-11-15(12-7-3-4-8-13(12)22)27(20(26)23-18)14-9-5-6-10-16(14)30-2/h3-11H,1-2H3,(H,24,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...				J Med Chem 56: 84-96 (2013) Article DOI: 10.1021/jm301187e BindingDB Entry DOI: 10.7270/Q2WW7K1S
					More data for this Ligand-Target Pair