Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM133688'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM133688 (US8846699, 4) Show SMILES NC(=O)N1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2NC(=O)C=C)CC1 Show InChI InChI=1S/C24H24BrFN6O3/c1-2-22(33)30-20-10-16-19(11-21(20)35-12-14-5-7-32(8-6-14)24(27)34)28-13-29-23(16)31-18-4-3-15(25)9-17(18)26/h2-4,9-11,13-14H,1,5-8,12H2,(H2,27,34)(H,30,33)(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	25
Hanmi Pharm. Co., Ltd. US Patent					Assay Description EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...				US Patent US8846699 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DRK
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