Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM318900'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM318900 (N-(3-(2-((4-(2-hydroxyethoxy)phenyl)amino)quinazol...) Show SMILES OCCOc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1 Show InChI InChI=1S/C25H22N4O3/c1-2-23(31)27-20-7-3-5-17(15-20)22-8-4-6-18-16-26-25(29-24(18)22)28-19-9-11-21(12-10-19)32-14-13-30/h2-12,15-16,30H,1,13-14H2,(H,27,31)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NEUPHARMA, INC. US Patent					Assay Description The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...				US Patent US10172868 (2019) BindingDB Entry DOI: 10.7270/Q25141BX
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM318900 (N-(3-(2-((4-(2-hydroxyethoxy)phenyl)amino)quinazol...) Show SMILES OCCOc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1 Show InChI InChI=1S/C25H22N4O3/c1-2-23(31)27-20-7-3-5-17(15-20)22-8-4-6-18-16-26-25(29-24(18)22)28-19-9-11-21(12-10-19)32-14-13-30/h2-12,15-16,30H,1,13-14H2,(H,27,31)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description EGFR: The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM MgCl2, 4 mM MnCl2, 1 mM EGTA, 2 mM DTT. The final 10 ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2571G7W
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM318900 (N-(3-(2-((4-(2-hydroxyethoxy)phenyl)amino)quinazol...) Show SMILES OCCOc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1 Show InChI InChI=1S/C25H22N4O3/c1-2-23(31)27-20-7-3-5-17(15-20)22-8-4-6-18-16-26-25(29-24(18)22)28-19-9-11-21(12-10-19)32-14-13-30/h2-12,15-16,30H,1,13-14H2,(H,27,31)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NEUPHARMA, INC. US Patent					Assay Description (i) Peptide/Kinase Mixtures for measurement of EGFR (ErbB1):The 2×EGFR (ErbB1)/Tyr 04 mixture is prepared in 50 mM HEPES pH 7.5, 0.01% BRIJ-35, 10 mM...				US Patent US10653701 (2020) BindingDB Entry DOI: 10.7270/Q2TB19XQ
					More data for this Ligand-Target Pair