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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50192500'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50192500
PNG
((3-bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5H-2...)
Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Nc2cc1OC
Show InChI InChI=1S/C19H18BrN5O2/c1-26-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)25-14(11)8-16(15)27-2/h3-8,10,21H,9H2,1-2H3,(H2,22,23,24,25)
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KEGG

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PC cid
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Similars
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



ImClone Systems Inc

Curated by ChEMBL


Assay Description
Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay

Bioorg Med Chem Lett 16: 5102-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.031
BindingDB Entry DOI: 10.7270/Q2K9374T
More data for this
Ligand-Target Pair