Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50234192'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50234192 (CHEMBL4073062) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n([C@@H]3CCN(C3)C(=O)C=C)c2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C27H33N7O3/c1-5-24(35)33-9-8-20(17-33)34-25(36)14-18(2)21-16-28-27(30-26(21)34)29-22-7-6-19(15-23(22)37-4)32-12-10-31(3)11-13-32/h5-7,14-16,20H,1,8-13,17H2,2-4H3,(H,28,29,30)/t20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 126: 1107-1117 (2017) Article DOI: 10.1016/j.ejmech.2016.12.006 BindingDB Entry DOI: 10.7270/Q2F47RD5
					More data for this Ligand-Target Pair