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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50457969'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50457969
PNG
(CHEMBL4206585)
Show SMILES CCS(=O)(=O)Nc1cc(cnc1OC)-c1ccc2ncnc(Nc3cccc(c3)C(=O)OC)c2c1
Show InChI InChI=1S/C24H23N5O5S/c1-4-35(31,32)29-21-12-17(13-25-23(21)33-2)15-8-9-20-19(11-15)22(27-14-26-20)28-18-7-5-6-16(10-18)24(30)34-3/h5-14,29H,4H2,1-3H3,(H,26,27,28)
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KEGG

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PC cid
PC sid
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Article
PubMed
n/an/a 409n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition and measured after...

Eur J Med Chem 146: 460-470 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.081
BindingDB Entry DOI: 10.7270/Q2NZ8B7G
More data for this
Ligand-Target Pair