BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50468494'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50468494
PNG
(CHEMBL4288374)
Show SMILES FC(F)(F)c1cccc(Oc2ccc(Nc3ncnc4sc(cc34)-c3ccc(NC(=O)NCCN4CCOCC4)cc3)cc2Cl)c1
Show InChI InChI=1S/C32H28ClF3N6O3S/c33-26-17-23(8-9-27(26)45-24-3-1-2-21(16-24)32(34,35)36)40-29-25-18-28(46-30(25)39-19-38-29)20-4-6-22(7-5-20)41-31(43)37-10-11-42-12-14-44-15-13-42/h1-9,16-19H,10-15H2,(H2,37,41,43)(H,38,39,40)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Ain Shams University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells u...

Eur J Med Chem 155: 316-336 (2018)


Article DOI: 10.1016/j.ejmech.2018.06.011
BindingDB Entry DOI: 10.7270/Q2K93B6Z
More data for this
Ligand-Target Pair