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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50468495'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50468495
PNG
(CHEMBL4280835)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc2c(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)ncnc2s1
Show InChI InChI=1S/C26H18ClF3N4O3S2/c1-39(35,36)34-17-7-5-15(6-8-17)23-13-20-24(31-14-32-25(20)38-23)33-18-9-10-22(21(27)12-18)37-19-4-2-3-16(11-19)26(28,29)30/h2-14,34H,1H3,(H,31,32,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Ain Shams University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells u...

Eur J Med Chem 155: 316-336 (2018)


Article DOI: 10.1016/j.ejmech.2018.06.011
BindingDB Entry DOI: 10.7270/Q2K93B6Z
More data for this
Ligand-Target Pair