Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50585313 (CHEMBL5087994) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 397 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of EGFR T790M/C797S double mutant (unknown origin) using flurogenic substrate in presence of ATP by HTRF assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113984 BindingDB Entry DOI: 10.7270/Q2M330PB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50585313 (CHEMBL5087994) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of EGFR del19 (unknown origin) using flurogenic substrate in presence of ATP by HTRF assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113984 BindingDB Entry DOI: 10.7270/Q2M330PB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50585313 (CHEMBL5087994) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of wild type EGFR (unknown origin) using flurogenic substrate in presence of ATP by HTRF assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113984 BindingDB Entry DOI: 10.7270/Q2M330PB | |||||||||||
More data for this Ligand-Target Pair |