Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Equilibrative nucleoside transporter 1 (Homo sapiens (Human)) | BDBM50240561![]() ((2R,3R,4S,5R)-2-(6-(benzylthio)-9H-purin-9-yl)-5-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Sciences Center Curated by ChEMBL | Assay Description Inhibition of human ENT1 | Bioorg Med Chem Lett 19: 314-8 (2008) Article DOI: 10.1016/j.bmcl.2008.11.092 BindingDB Entry DOI: 10.7270/Q2H996F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative nucleoside transporter 1 (Homo sapiens (Human)) | BDBM50240561![]() ((2R,3R,4S,5R)-2-(6-(benzylthio)-9H-purin-9-yl)-5-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranes | J Med Chem 48: 321-9 (2005) Article DOI: 10.1021/jm049303k BindingDB Entry DOI: 10.7270/Q29024J0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative nucleoside transporter 1 (Homo sapiens (Human)) | BDBM50240561![]() ((2R,3R,4S,5R)-2-(6-(benzylthio)-9H-purin-9-yl)-5-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Binding affinity to ENT1 transporter | Bioorg Med Chem 16: 3848-65 (2008) Article DOI: 10.1016/j.bmc.2008.01.044 BindingDB Entry DOI: 10.7270/Q2GM8866 | |||||||||||
More data for this Ligand-Target Pair |