BindingDB PrimarySearch

Found 1 hit Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50309559'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50309559 (CHEMBL606169) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL	Assay Description Estrogenic activity at ERalpha in human Ishikawa cells assessed as stimulation of alkaline phosphatase activity after 4 days by microplate scanning s...	Bioorg Med Chem 18: 809-21 (2010) Article DOI: 10.1016/j.bmc.2009.11.046 BindingDB Entry DOI: 10.7270/Q28K797G
More data for this Ligand-Target Pair

Estrogen receptor

(Homo sapiens (Human))

(CHEMBL606169)

Show InChI InChI=1S/C373H433N35O49/c1-37-374-137-121-214-153-215-167-291(375-38-2)194(17)140-271(215)318(270(214)139-193(15)16)256-65-51-58-72-263(256)346(423)437-228-86-100-236-208(160-228)80-94-250-243(236)108-126-363(33)287(250)117-133-370(363,433)314-189-405(398-391-314)182-307-342-329(413)336(420)357(448-307)456-344-309(184-407-191-316(393-400-407)372(435)135-119-289-254-98-84-212-165-233(91-105-240(212)247(254)112-128-365(289,372)35)442-351(428)268-77-63-56-70-261(268)323-280-149-203(26)300(384-47-11)176-224(280)158-225-177-301(385-48-12)204(27)150-281(225)323)450-359(338(422)331(344)415)457-345-310(185-408-192-317(394-401-408)373(436)136-120-290-255-99-85-213-166-234(92-106-241(213)248(255)113-129-366(290,373)36)443-352(429)269-78-64-57-71-262(269)324-282-151-205(28)302(386-49-13)178-226(282)159-227-179-303(387-50-14)206(29)152-283(227)324)449-358(337(421)330(345)414)455-343-308(183-406-190-315(392-399-406)371(434)134-118-288-253-97-83-211-164-232(90-104-239(211)246(253)111-127-364(288,371)34)441-350(427)267-76-62-55-69-260(267)322-278-147-201(24)298(382-45-9)174-222(278)157-223-175-299(383-46-10)202(25)148-279(223)322)447-356(335(419)328(343)412)453-341-306(181-404-188-313(390-397-404)369(432)132-116-286-252-96-82-210-163-231(89-103-238(210)245(252)110-125-362(286,369)32)440-349(426)266-75-61-54-68-259(266)321-276-145-199(22)296(380-43-7)172-220(276)156-221-173-297(381-44-8)200(23)146-277(221)321)445-354(333(417)326(341)410)451-339-304(122-138-402-186-311(388-395-402)367(430)130-114-284-249-93-79-207-161-229(87-101-235(207)242(249)107-123-360(284,367)30)438-347(424)264-73-59-52-66-257(264)319-272-141-195(18)292(376-39-3)168-216(272)154-217-169-293(377-40-4)196(19)142-273(217)319)444-353(332(416)325(339)409)452-340-305(446-355(454-342)334(418)327(340)411)180-403-187-312(389-396-403)368(431)131-115-285-251-95-81-209-162-230(88-102-237(209)244(251)109-124-361(285,368)31)439-348(425)265-74-60-53-67-258(265)320-274-143-197(20)294(378-41-5)170-218(274)155-219-171-295(379-42-6)198(21)144-275(219)320/h51-78,86-92,100-106,137,139-152,160-179,186-192,242-255,284-290,304-310,318-345,353-359,375-387,409-422,430-436H,37-50,79-85,93-99,107-136,138,153-159,180-185H2,1-36H3/t242-,243-,244-,245-,246-,247-,248-,249-,250-,251-,252-,253-,254-,255-,284+,285+,286+,287+,288+,289+,290+,304-,305-,306-,307-,308-,309-,310-,318?,325-,326-,327-,328-,329-,330-,331-,332-,333-,334-,335-,336-,337-,338-,339-,340-,341-,342-,343-,344-,345-,353-,354-,355-,356-,357-,358-,359-,360+,361+,362+,363+,364+,365+,366+,367-,368-,369-,370-,371-,372-,373-/m1/s1

PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed

n/a

2.60E+3

n/a

University of Illinois at Chicago

Curated by ChEMBL

Assay Description
Estrogenic activity at ERalpha in human Ishikawa cells assessed as stimulation of alkaline phosphatase activity after 4 days by microplate scanning s...

Bioorg Med Chem 18: 809-21 (2010)

Article DOI: 10.1016/j.bmc.2009.11.046
BindingDB Entry DOI: 10.7270/Q28K797G

More data for this
Ligand-Target Pair