Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor [Y537S] (Homo sapiens (Human)) | BDBM443446 (US10654866, Example 5B | US11117902, Example 5A | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company US Patent | Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT... | US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor [Y537S] (Homo sapiens (Human)) | BDBM443446 (US10654866, Example 5B | US11117902, Example 5A | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 6.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor [Y537S] (Homo sapiens (Human)) | BDBM443446 (US10654866, Example 5B | US11117902, Example 5A | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 81.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5... | Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M | |||||||||||
More data for this Ligand-Target Pair |