BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Estrogen receptor beta' and Ligand = 'BDBM50154045'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor beta (Rattus norvegicus)	BDBM50154045 (5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...) Show SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coli				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Mus musculus)	BDBM50154045 (5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...) Show SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coli				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154045 (5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...) Show SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154045 (5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...) Show SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Yantai University Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin)				Eur J Med Chem 43: 43-52 (2008) Article DOI: 10.1016/j.ejmech.2007.03.002 BindingDB Entry DOI: 10.7270/Q2WD40BT
Yantai University Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50154045 (5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...) Show SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF
TBA					More data for this Ligand-Target Pair