Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM22438 (4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | 7.0 | 22 |
GSK | Assay Description Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra... | J Med Chem 48: 3107-9 (2005) Article DOI: 10.1021/jm050161j BindingDB Entry DOI: 10.7270/Q2S46Q77 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM22438 (4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Agonist activity at Gal4 fused ERRgamma-LBD (unknown origin) expressed in HEK293T cells after 20 hrs by UAS-luciferase reporter gene assay | Bioorg Med Chem Lett 28: 1313-1319 (2018) Article DOI: 10.1016/j.bmcl.2018.03.019 BindingDB Entry DOI: 10.7270/Q2RF5XKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM22438 (4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 600 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Agonist activity at human N-terminal alphaHis-SUMO-tagged ERRgamma-LBD (229 to 458 residues) expressed in Escherichia coli BL21 gold (DE3) cells asse... | Bioorg Med Chem Lett 28: 1313-1319 (2018) Article DOI: 10.1016/j.bmcl.2018.03.019 BindingDB Entry DOI: 10.7270/Q2RF5XKM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM22438 (4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL | Assay Description Binding affinity to ERRgamma (unknown origin) at 20 degC by isothermal titration calorimetry | Bioorg Med Chem 23: 3751-60 (2015) Article DOI: 10.1016/j.bmc.2015.03.082 BindingDB Entry DOI: 10.7270/Q2222WJM | |||||||||||
More data for this Ligand-Target Pair |