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Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50175367'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50175367
PNG
((R)-1-(2,3-dichlorophenylthio)-3-(1-(4-fluoropheny...)
Show SMILES CC(C)(Cc1ccc(F)cc1)NC[C@@H](O)CSc1cccc(Cl)c1Cl
Show InChI InChI=1S/C19H22Cl2FNOS/c1-19(2,10-13-6-8-14(22)9-7-13)23-11-15(24)12-25-17-5-3-4-16(20)18(17)21/h3-9,15,23-24H,10-12H2,1-2H3/t15-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.18E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR

Bioorg Med Chem Lett 15: 5478-82 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.095
BindingDB Entry DOI: 10.7270/Q2WS8STX
More data for this
Ligand-Target Pair