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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50175372'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50175372
PNG
((R)-1-((R)-1-(3-methoxybenzyl)pyrrolidin-2-yl)-2-(...)
Show SMILES COc1cccc(CN2CCC[C@@H]2[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C28H36N2O2/c1-28(2,18-21-13-14-23-9-4-5-10-24(23)16-21)29-19-27(31)26-12-7-15-30(26)20-22-8-6-11-25(17-22)32-3/h4-6,8-11,13-14,16-17,26-27,29,31H,7,12,15,18-20H2,1-3H3/t26-,27-/m1/s1
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PC sid
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Similars
Article
PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR

Bioorg Med Chem Lett 15: 5478-82 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.095
BindingDB Entry DOI: 10.7270/Q2WS8STX
More data for this
Ligand-Target Pair