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Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50175389'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50175389
PNG
((S)-1-(2-methyl-1-phenylpropan-2-ylamino)-3-(2-(me...)
Show SMILES CC(C)(Cc1ccccc1)NC[C@H](O)COc1ccccc1S(C)(=O)=O
Show InChI InChI=1S/C20H27NO4S/c1-20(2,13-16-9-5-4-6-10-16)21-14-17(22)15-25-18-11-7-8-12-19(18)26(3,23)24/h4-12,17,21-22H,13-15H2,1-3H3/t17-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.43E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR

Bioorg Med Chem Lett 15: 5478-82 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.095
BindingDB Entry DOI: 10.7270/Q2WS8STX
More data for this
Ligand-Target Pair