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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50261660'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50261660
PNG
(CHEMBL4070562)
Show SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)C(=O)N[C@H](CCCCN)C(O)=O)c1cccc2ccccc12 |r|
Show InChI InChI=1S/C29H36N4O3/c1-20(25-10-6-8-21-7-2-3-9-26(21)25)31-23-16-18-33(19-23)24-14-12-22(13-15-24)28(34)32-27(29(35)36)11-4-5-17-30/h2-3,6-10,12-15,20,23,27,31H,4-5,11,16-19,30H2,1H3,(H,32,34)(H,35,36)/t20-,23+,27-/m1/s1
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Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Enteroendocrine Discovery Performance Unit and Platform Technologies and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, United States. Electronic address: ssparks@viamet.c

Curated by ChEMBL


Assay Description
Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...

Bioorg Med Chem Lett 27: 4673-4677 (2017)


Article DOI: 10.1016/j.bmcl.2017.09.008
BindingDB Entry DOI: 10.7270/Q29889FR
More data for this
Ligand-Target Pair