BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Eyes absent homolog 3' and Ligand = 'BDBM50342287'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eyes absent homolog 3


(Homo sapiens (Human))
BDBM50342287
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Show SMILES CCc1oc2ccc(O)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-7-9(20)3-4-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.08E+4n/an/an/an/an/an/a



GNF



Assay Description
The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...


Bioorg Med Chem Lett 16: 5488-92 (2006)


BindingDB Entry DOI: 10.7270/Q2ZK5JZ7
More data for this
Ligand-Target Pair
Eyes absent homolog 3


(Homo sapiens (Human))
BDBM50342287
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Show SMILES CCc1oc2ccc(O)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-7-9(20)3-4-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.08E+4n/an/an/an/an/an/a



CHILDREN HOSPITAL MEDICAL CENTER

US Patent


Assay Description
An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....


US Patent US9725430 (2017)


BindingDB Entry DOI: 10.7270/Q23F4RSZ
More data for this
Ligand-Target Pair