Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50256128'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Rattus norvegicus)	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacology & Toxicology Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat liver fatty acid synthase				Bioorg Med Chem Lett 19: 770-2 (2009) Article DOI: 10.1016/j.bmcl.2008.12.010 BindingDB Entry DOI: 10.7270/Q2F76CFQ
					More data for this Ligand-Target Pair
Fatty acid synthase (Rattus norvegicus)	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Curated by ChEMBL					Assay Description Inhibition of rat liver FAS by Coomassie blue staining				Bioorg Med Chem 17: 1898-904 (2009) Article DOI: 10.1016/j.bmc.2009.01.050 BindingDB Entry DOI: 10.7270/Q22F7NBQ
					More data for this Ligand-Target Pair
Fatty acid synthase (Homo sapiens (Human))	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of FASN in human A375 cells				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
					More data for this Ligand-Target Pair
Fatty acid synthase (Homo sapiens (Human))	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant FASN thioesterase domain				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
					More data for this Ligand-Target Pair
Fatty acid synthase (Gallus gallus (Chicken))	BDBM50256128 ((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...) Show SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O |r| Show InChI InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of chicken liver FASN ketoreductase activity				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
					More data for this Ligand-Target Pair