Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM286986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM286986 (8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccccc3)nc2n(CCCN2CCN(CC2)C(=O)C=C)c1=O Show InChI InChI=1S/C31H33ClN6O4/c1-4-27(39)37-15-13-36(14-16-37)11-8-12-38-29-21(20-33-31(35-29)34-22-9-6-5-7-10-22)17-25(30(38)40)24-18-23(41-2)19-26(42-3)28(24)32/h4-7,9-10,17-20H,1,8,11-16H2,2-3H3,(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	25
Principia Biopharma, Inc. US Patent					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				US Patent US9567334 (2017) BindingDB Entry DOI: 10.7270/Q2XK8HKQ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM286986 (8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccccc3)nc2n(CCCN2CCN(CC2)C(=O)C=C)c1=O Show InChI InChI=1S/C31H33ClN6O4/c1-4-27(39)37-15-13-36(14-16-37)11-8-12-38-29-21(20-33-31(35-29)34-22-9-6-5-7-10-22)17-25(30(38)40)24-18-23(41-2)19-26(42-3)28(24)32/h4-7,9-10,17-20H,1,8,11-16H2,2-3H3,(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DB850W
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM286986 (8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccccc3)nc2n(CCCN2CCN(CC2)C(=O)C=C)c1=O Show InChI InChI=1S/C31H33ClN6O4/c1-4-27(39)37-15-13-36(14-16-37)11-8-12-38-29-21(20-33-31(35-29)34-22-9-6-5-7-10-22)17-25(30(38)40)24-18-23(41-2)19-26(42-3)28(24)32/h4-7,9-10,17-20H,1,8,11-16H2,2-3H3,(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q2GX4DVZ
					More data for this Ligand-Target Pair