Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM287074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM287074 (8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-2-amino-...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(N)nc2n(CCOC2CN(C2)C(=O)C=C)c1=O Show InChI InChI=1S/C23H24ClN5O5/c1-4-19(30)28-11-15(12-28)34-6-5-29-21-13(10-26-23(25)27-21)7-17(22(29)31)16-8-14(32-2)9-18(33-3)20(16)24/h4,7-10,15H,1,5-6,11-12H2,2-3H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	25
Principia Biopharma, Inc. US Patent					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				US Patent US9567334 (2017) BindingDB Entry DOI: 10.7270/Q2XK8HKQ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM287074 (8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-2-amino-...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(N)nc2n(CCOC2CN(C2)C(=O)C=C)c1=O Show InChI InChI=1S/C23H24ClN5O5/c1-4-19(30)28-11-15(12-28)34-6-5-29-21-13(10-26-23(25)27-21)7-17(22(29)31)16-8-14(32-2)9-18(33-3)20(16)24/h4,7-10,15H,1,5-6,11-12H2,2-3H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DB850W
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM287074 (8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-2-amino-...) Show SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(N)nc2n(CCOC2CN(C2)C(=O)C=C)c1=O Show InChI InChI=1S/C23H24ClN5O5/c1-4-19(30)28-11-15(12-28)34-6-5-29-21-13(10-26-23(25)27-21)7-17(22(29)31)16-8-14(32-2)9-18(33-3)20(16)24/h4,7-10,15H,1,5-6,11-12H2,2-3H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q2GX4DVZ
					More data for this Ligand-Target Pair