Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM511139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM511139 (US11078199, Cpd 163) Show SMILES CNc1ncc2cc(-c3c(Cl)c(O)cc(OC)c3Cl)c(=O)n(CCCN3CCN(CC3)C(=O)C=C)c2n1 |(6.67,-.77,;5.33,,;4,-.77,;4,-2.31,;2.67,-3.08,;1.33,-2.31,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;-2.67,-4.62,;-1.33,-5.39,;-4,-5.39,;-4,-6.93,;-5.33,-4.62,;-5.33,-3.08,;-6.67,-2.31,;-8,-3.08,;-4,-2.31,;-4,-.77,;-1.33,-.77,;-2.67,,;;,1.54,;1.33,2.31,;1.33,3.85,;2.67,4.62,;4,3.85,;5.33,4.62,;5.33,6.16,;4,6.93,;2.67,6.16,;6.67,6.93,;8,6.16,;6.67,8.47,;8,9.24,;1.33,-.77,;2.67,,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DB850W
					More data for this Ligand-Target Pair