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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1 [308-731]' and Ligand = 'BDBM350042'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 1 [308-731]


(Homo sapiens (Human))		BDBM350042
PNG
(US10208024, Example 41 | US10766881, Example 41)
Show SMILES COc1cc(OC)c(F)c(c1)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H25FN8O3/c1-35-16-9-19(22(25)20(10-16)36-2)33-21(34)4-3-17(31-33)23-24(26)28-12-18(30-23)14-11-29-32(13-14)15-5-7-27-8-6-15/h3-4,9-13,15,27H,5-8H2,1-2H3,(H2,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Array Biopharma Inc.

US Patent


Assay Description
To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...

US Patent US10766881 (2020)


BindingDB Entry DOI: 10.7270/Q2BZ693Q
More data for this
Ligand-Target Pair