Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1 [308-731]' and Ligand = 'BDBM350082'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 [308-731] (Homo sapiens (Human))	BDBM350082 (US10208024, Example 81 | US10766881, Example 81) Show SMILES COc1cc(OC)cc(c1)-n1nc(cc(C)c1=O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H29N7O3/c1-16-8-24(31-33(26(16)34)20-10-21(35-2)12-22(11-20)36-3)23-9-17(13-29-25(23)27)18-14-30-32(15-18)19-4-6-28-7-5-19/h8-15,19,28H,4-7H2,1-3H3,(H2,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Array Biopharma Inc. US Patent					Assay Description To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...				US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q
					More data for this Ligand-Target Pair