Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM130806'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM130806 (US8829199, 27) Show SMILES Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3cc(ccc3[nH]2)C(=O)N2CCCC(F)(F)C2)c1N Show InChI InChI=1S/C26H23F2N7O2/c1-14-31-20-6-4-17(11-21(20)32-14)35-24(29)18(12-30-35)23(36)22-10-16-9-15(3-5-19(16)33-22)25(37)34-8-2-7-26(27,28)13-34/h3-6,9-12,33H,2,7-8,13,29H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha; F. Hoffmann-La Roche AG US Patent					Assay Description The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...				US Patent US8829199 (2014) BindingDB Entry DOI: 10.7270/Q26T0KB8
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