Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM130892'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM130892 (US8829199, 185) Show SMILES COc1cc2[nH]c(cc2cc1Cl)C(=O)c1cnn(c1N)-c1ccc2nc(C)nc2c1 Show InChI InChI=1S/C21H17ClN6O2/c1-10-25-15-4-3-12(7-17(15)26-10)28-21(23)13(9-24-28)20(29)18-6-11-5-14(22)19(30-2)8-16(11)27-18/h3-9,27H,23H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha; F. Hoffmann-La Roche AG US Patent					Assay Description The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...				US Patent US8829199 (2014) BindingDB Entry DOI: 10.7270/Q26T0KB8
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