Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM161437'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161437 (US10124003, Ex. Compound 50 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CCCCC2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C29H34N6O3/c1-37-24-15-21(16-25(17-24)38-2)8-9-22-18-35(29-27(22)28(30)31-20-32-29)23-10-14-34(19-23)26(36)7-6-13-33-11-4-3-5-12-33/h6-7,15-18,20,23H,3-5,10-14,19H2,1-2H3,(H2,30,31,32)/b7-6+/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161437 (US10124003, Ex. Compound 50 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CCCCC2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C29H34N6O3/c1-37-24-15-21(16-25(17-24)38-2)8-9-22-18-35(29-27(22)28(30)31-20-32-29)23-10-14-34(19-23)26(36)7-6-13-33-11-4-3-5-12-33/h6-7,15-18,20,23H,3-5,10-14,19H2,1-2H3,(H2,30,31,32)/b7-6+/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161437 (US10124003, Ex. Compound 50 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CCCCC2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C29H34N6O3/c1-37-24-15-21(16-25(17-24)38-2)8-9-22-18-35(29-27(22)28(30)31-20-32-29)23-10-14-34(19-23)26(36)7-6-13-33-11-4-3-5-12-33/h6-7,15-18,20,23H,3-5,10-14,19H2,1-2H3,(H2,30,31,32)/b7-6+/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161437 (US10124003, Ex. Compound 50 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CCCCC2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C29H34N6O3/c1-37-24-15-21(16-25(17-24)38-2)8-9-22-18-35(29-27(22)28(30)31-20-32-29)23-10-14-34(19-23)26(36)7-6-13-33-11-4-3-5-12-33/h6-7,15-18,20,23H,3-5,10-14,19H2,1-2H3,(H2,30,31,32)/b7-6+/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair