Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM287519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM287519 (8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...) Show SMILES CCN1CCN(CCCNc2ncc3cc(-c4c(Cl)c(OC)cc(OC)c4Cl)c(=O)n(CCOC4CN(C4)C(=O)C=C)c3n2)CC1 |(-10.28,-8.09,;-10.28,-6.55,;-8.95,-5.78,;-8.95,-4.24,;-7.61,-3.47,;-6.28,-4.24,;-4.94,-3.47,;-4.94,-1.93,;-3.61,-1.16,;-3.61,.38,;-2.28,1.15,;-2.28,2.69,;-.94,3.46,;.39,2.69,;1.72,3.46,;3.06,2.69,;4.39,3.46,;4.39,5,;3.06,5.77,;5.73,5.78,;5.73,7.32,;7.06,8.09,;7.06,5,;7.06,3.46,;8.39,2.69,;9.73,3.46,;5.73,2.69,;5.73,1.15,;3.06,1.15,;4.39,.38,;1.72,.38,;1.72,-1.16,;3.06,-1.93,;3.06,-3.47,;4.39,-4.24,;4.79,-5.72,;6.28,-5.32,;5.88,-3.84,;7.61,-6.09,;7.61,-7.63,;8.95,-5.32,;10.28,-6.09,;.39,1.15,;-.94,.38,;-6.28,-5.78,;-7.61,-6.55,)| Show InChI InChI=1S/C32H41Cl2N7O5/c1-5-26(42)40-19-22(20-40)46-15-14-41-30-21(16-23(31(41)43)27-28(33)24(44-3)17-25(45-4)29(27)34)18-36-32(37-30)35-8-7-9-39-12-10-38(6-2)11-13-39/h5,16-18,22H,1,6-15,19-20H2,2-4H3,(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...				Bioorg Med Chem Lett 19: 773-7 (2009) BindingDB Entry DOI: 10.7270/Q2GX4DVZ
					More data for this Ligand-Target Pair