Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM298365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298365 (US10124003, Ex. Compound 38 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN(C)C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C26H30N6O3/c1-30(2)10-5-6-23(33)31-11-9-20(16-31)32-15-19(24-25(27)28-17-29-26(24)32)8-7-18-12-21(34-3)14-22(13-18)35-4/h5-6,12-15,17,20H,9-11,16H2,1-4H3,(H2,27,28,29)/b6-5+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298365 (US10124003, Ex. Compound 38 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN(C)C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C26H30N6O3/c1-30(2)10-5-6-23(33)31-11-9-20(16-31)32-15-19(24-25(27)28-17-29-26(24)32)8-7-18-12-21(34-3)14-22(13-18)35-4/h5-6,12-15,17,20H,9-11,16H2,1-4H3,(H2,27,28,29)/b6-5+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298365 (US10124003, Ex. Compound 38 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN(C)C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C26H30N6O3/c1-30(2)10-5-6-23(33)31-11-9-20(16-31)32-15-19(24-25(27)28-17-29-26(24)32)8-7-18-12-21(34-3)14-22(13-18)35-4/h5-6,12-15,17,20H,9-11,16H2,1-4H3,(H2,27,28,29)/b6-5+/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair