Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM448234'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM448234 (US10689705, Compound 11) Show SMILES CC(C)N1CCC(CC1)c1ccc2[nH]c(cc2c1)C(=O)c1cnn(c1N)-c1ccc2nc(C)[nH]c2c1 Show InChI InChI=1S/C28H31N7O/c1-16(2)34-10-8-18(9-11-34)19-4-6-23-20(12-19)13-26(33-23)27(36)22-15-30-35(28(22)29)21-5-7-24-25(14-21)32-17(3)31-24/h4-7,12-16,18,33H,8-11,29H2,1-3H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha US Patent					Assay Description The FGFR2 inhibitory activities of compounds listed in Tables 1-1 to 1-5 were measured based on their activity to inhibit phosphorylation of the biot...				US Patent US10689705 (2020) BindingDB Entry DOI: 10.7270/Q2CV4MSX
					More data for this Ligand-Target Pair