Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM448237'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM448237 (US10689705, Compound 14) Show SMILES Cc1nc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3cc4OCCOc4cc3[nH]2)c1N Show InChI InChI=1S/C22H18N6O3/c1-11-25-15-3-2-13(8-17(15)26-11)28-22(23)14(10-24-28)21(29)18-6-12-7-19-20(9-16(12)27-18)31-5-4-30-19/h2-3,6-10,27H,4-5,23H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha US Patent					Assay Description The FGFR2 inhibitory activities of compounds listed in Tables 1-1 to 1-5 were measured based on their activity to inhibit phosphorylation of the biot...				US Patent US10689705 (2020) BindingDB Entry DOI: 10.7270/Q2CV4MSX
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