Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM448270'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM448270 (US10689705, Compound 47) Show SMILES Cc1nc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3cc(CN4CCN(CC4)S(C)(=O)=O)ccc3[nH]2)c1N Show InChI InChI=1S/C26H28N8O3S/c1-16-29-22-6-4-19(13-23(22)30-16)34-26(27)20(14-28-34)25(35)24-12-18-11-17(3-5-21(18)31-24)15-32-7-9-33(10-8-32)38(2,36)37/h3-6,11-14,31H,7-10,15,27H2,1-2H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha US Patent					Assay Description The FGFR2 inhibitory activities of compounds listed in Tables 1-1 to 1-5 were measured based on their activity to inhibit phosphorylation of the biot...				US Patent US10689705 (2020) BindingDB Entry DOI: 10.7270/Q2CV4MSX
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