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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM454184'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM454184
PNG
(US10717708, Example 48 | US11186544, Example 48 | ...)
Show SMILES NC(=O)c1ccc(cc1)-c1ccc(cc1)N1CCCC(NC(=O)Nc2ccc(cc2)C(F)(F)F)C1=O
Show InChI InChI=1S/C26H23F3N4O3/c27-26(28,29)19-9-11-20(12-10-19)31-25(36)32-22-2-1-15-33(24(22)35)21-13-7-17(8-14-21)16-3-5-18(6-4-16)23(30)34/h3-14,22H,1-2,15H2,(H2,30,34)(H2,31,32,36)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 560n/an/an/an/a


TBA

Assay Description
A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VQ36JD
More data for this
Ligand-Target Pair