Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102502'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102502 (US8536175, 3) Show SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(cc2)C(N)=O)c2nccnc12 |(9.24,-2.67,;7.7,-2.67,;6.93,-1.33,;7.7,,;6.93,1.33,;7.7,2.67,;6.93,4,;5.39,1.33,;4.62,2.67,;4.62,,;5.39,-1.33,;4.62,-2.67,;3.08,,;2.31,1.33,;.77,1.33,;;-1.54,,;-2.31,1.33,;-2.31,-1.33,;-3.85,-1.33,;-4.62,,;-6.16,,;-6.93,-1.33,;-6.16,-2.67,;-4.62,-2.67,;-8.47,-1.33,;-9.24,-2.67,;-9.24,,;.77,-1.33,;,-2.67,;.77,-4,;2.31,-4,;3.08,-2.67,;2.31,-1.33,)| Show InChI InChI=1S/C24H18Cl2N4O4/c1-33-16-11-17(34-2)20(26)18(19(16)25)14-7-8-15(22-21(14)28-9-10-29-22)24(32)30-13-5-3-12(4-6-13)23(27)31/h3-11H,1-2H3,(H2,27,31)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102502 (US8536175, 3) Show SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(cc2)C(N)=O)c2nccnc12 |(9.24,-2.67,;7.7,-2.67,;6.93,-1.33,;7.7,,;6.93,1.33,;7.7,2.67,;6.93,4,;5.39,1.33,;4.62,2.67,;4.62,,;5.39,-1.33,;4.62,-2.67,;3.08,,;2.31,1.33,;.77,1.33,;;-1.54,,;-2.31,1.33,;-2.31,-1.33,;-3.85,-1.33,;-4.62,,;-6.16,,;-6.93,-1.33,;-6.16,-2.67,;-4.62,-2.67,;-8.47,-1.33,;-9.24,-2.67,;-9.24,,;.77,-1.33,;,-2.67,;.77,-4,;2.31,-4,;3.08,-2.67,;2.31,-1.33,)| Show InChI InChI=1S/C24H18Cl2N4O4/c1-33-16-11-17(34-2)20(26)18(19(16)25)14-7-8-15(22-21(14)28-9-10-29-22)24(32)30-13-5-3-12(4-6-13)23(27)31/h3-11H,1-2H3,(H2,27,31)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair