Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102508'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102508 (US8536175, 20) Show SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ncc(CN3CCN(C)CC3)[nH]2)c2nccnc12 |(11.06,-2.67,;9.52,-2.67,;8.75,-1.33,;9.52,,;8.75,1.33,;9.52,2.67,;8.75,4,;7.21,1.33,;6.44,2.67,;6.44,,;7.21,-1.33,;6.44,-2.67,;4.9,,;4.13,1.33,;2.59,1.33,;1.82,,;.28,,;-.49,1.33,;-.49,-1.33,;-2.03,-1.33,;-2.93,-.09,;-4.4,-.56,;-4.4,-2.1,;-5.73,-2.87,;-7.06,-2.1,;-7.06,-.56,;-8.4,.21,;-9.73,-.56,;-11.06,.21,;-9.73,-2.1,;-8.4,-2.87,;-2.93,-2.58,;2.59,-1.33,;1.82,-2.67,;2.59,-4,;4.13,-4,;4.9,-2.67,;4.13,-1.33,)| Show InChI InChI=1S/C26H27Cl2N7O3/c1-34-8-10-35(11-9-34)14-15-13-31-26(32-15)33-25(36)17-5-4-16(23-24(17)30-7-6-29-23)20-21(27)18(37-2)12-19(38-3)22(20)28/h4-7,12-13H,8-11,14H2,1-3H3,(H2,31,32,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair