Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102518'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102518 (US8536175, 62 | US8815901, 62) Show SMILES CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4csc5ccccc45)c4nccnc34)[nH]2)CC1 Show InChI InChI=1S/C26H25N7OS/c1-32-10-12-33(13-11-32)15-17-14-29-26(30-17)31-25(34)20-7-6-19(23-24(20)28-9-8-27-23)21-16-35-22-5-3-2-4-18(21)22/h2-9,14,16H,10-13,15H2,1H3,(H2,29,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102518 (US8536175, 62 | US8815901, 62) Show SMILES CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4csc5ccccc45)c4nccnc34)[nH]2)CC1 Show InChI InChI=1S/C26H25N7OS/c1-32-10-12-33(13-11-32)15-17-14-29-26(30-17)31-25(34)20-7-6-19(23-24(20)28-9-8-27-23)21-16-35-22-5-3-2-4-18(21)22/h2-9,14,16H,10-13,15H2,1H3,(H2,29,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair