Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102525'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102525 (US8536175, 91) Show SMILES COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccccn2)c2nccnc12 |(8.09,-2.67,;6.55,-2.67,;5.78,-1.33,;6.55,,;5.78,1.33,;6.55,2.67,;5.78,4,;4.23,1.33,;3.47,2.67,;3.47,,;4.23,-1.33,;3.47,-2.67,;1.93,,;1.15,1.33,;-.38,1.33,;-1.15,,;-2.69,,;-3.47,1.33,;-3.47,-1.33,;-5,-1.33,;-5.78,,;-7.31,,;-8.08,-1.33,;-7.31,-2.67,;-5.78,-2.67,;-.38,-1.33,;-1.15,-2.67,;-.38,-4,;1.15,-4,;1.93,-2.67,;1.15,-1.33,)| Show InChI InChI=1S/C22H16F2N4O3/c1-30-14-11-15(31-2)19(24)17(18(14)23)12-6-7-13(21-20(12)26-9-10-27-21)22(29)28-16-5-3-4-8-25-16/h3-11H,1-2H3,(H,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102525 (US8536175, 91) Show SMILES COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccccn2)c2nccnc12 |(8.09,-2.67,;6.55,-2.67,;5.78,-1.33,;6.55,,;5.78,1.33,;6.55,2.67,;5.78,4,;4.23,1.33,;3.47,2.67,;3.47,,;4.23,-1.33,;3.47,-2.67,;1.93,,;1.15,1.33,;-.38,1.33,;-1.15,,;-2.69,,;-3.47,1.33,;-3.47,-1.33,;-5,-1.33,;-5.78,,;-7.31,,;-8.08,-1.33,;-7.31,-2.67,;-5.78,-2.67,;-.38,-1.33,;-1.15,-2.67,;-.38,-4,;1.15,-4,;1.93,-2.67,;1.15,-1.33,)| Show InChI InChI=1S/C22H16F2N4O3/c1-30-14-11-15(31-2)19(24)17(18(14)23)12-6-7-13(21-20(12)26-9-10-27-21)22(29)28-16-5-3-4-8-25-16/h3-11H,1-2H3,(H,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair