Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM102539'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102539 (US8536175, 143) Show SMILES COc1cc(OC)c(F)c(c1)-c1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cn2)c2nccnc12 Show InChI InChI=1S/C28H29FN6O3/c1-34-10-12-35(13-11-34)17-18-4-7-24(32-16-18)33-28(36)21-6-5-20(26-27(21)31-9-8-30-26)22-14-19(37-2)15-23(38-3)25(22)29/h4-9,14-16H,10-13,17H2,1-3H3,(H,32,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102539 (US8536175, 143) Show SMILES COc1cc(OC)c(F)c(c1)-c1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cn2)c2nccnc12 Show InChI InChI=1S/C28H29FN6O3/c1-34-10-12-35(13-11-34)17-18-4-7-24(32-16-18)33-28(36)21-6-5-20(26-27(21)31-9-8-30-26)22-14-19(37-2)15-23(38-3)25(22)29/h4-9,14-16H,10-13,17H2,1-3H3,(H,32,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair