Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM102218'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM102218 (US9695165, 20) Show SMILES CCn1c2cc(ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O)-c1cccc(NC(=O)C=C)c1 |(6,-.39,;4.67,-1.16,;3.33,-.39,;2,-1.16,;2,-2.7,;.67,-3.47,;-.67,-2.7,;-.67,-1.16,;.67,-.39,;.67,1.15,;2,1.92,;2,3.46,;.67,4.23,;-.67,3.46,;.67,5.77,;-.67,6.54,;-2,5.77,;2,6.54,;3.33,5.77,;4.67,6.55,;4.67,8.09,;3.33,4.23,;4.67,3.47,;3.33,1.15,;4.67,1.92,;.67,-5.01,;2,-5.78,;2,-7.32,;.67,-8.09,;-.67,-7.32,;-2,-8.09,;-3.33,-7.32,;-3.33,-5.78,;-4.67,-8.09,;-6,-7.32,;-.67,-5.78,)| Show InChI InChI=1S/C27H23Cl2N3O4/c1-5-23(33)31-17-9-7-8-15(10-17)19-12-20-16(14-30-19)11-18(27(34)32(20)6-2)24-25(28)21(35-3)13-22(36-4)26(24)29/h5,7-14H,1,6H2,2-4H3,(H,31,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...				US Patent US9695165 (2017) BindingDB Entry DOI: 10.7270/Q25M67QZ
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