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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM103607'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 4


(Homo sapiens (Human))
BDBM103607
PNG
(US9695165, 28)
Show SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(ncc2c1)-c1cc2N(CCOc2cc1F)C(=O)C=C
Show InChI InChI=1S/C27H20Cl2FN3O4/c1-4-23(34)33-7-8-37-20-11-17(30)16(10-19(20)33)27-31-13-15-9-14(5-6-18(15)32-27)24-25(28)21(35-2)12-22(36-3)26(24)29/h4-6,9-13H,1,7-8H2,2-3H3
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KEGG

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Similars

US Patent
n/an/a<10n/an/an/an/a7.525



BLUEPRINT MEDICINES CORPORATION

US Patent


Assay Description
In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...


US Patent US9695165 (2017)


BindingDB Entry DOI: 10.7270/Q25M67QZ
More data for this
Ligand-Target Pair