Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM103854'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM103854 (US9695165, 37) Show SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(cc2n(C)c1=O)-c1ccc2OCCN(C(=O)C=C)c2c1 |(-3.33,9.24,;-3.33,7.7,;-2,6.93,;-.67,7.7,;.67,6.93,;2,7.7,;3.33,6.93,;.67,5.39,;2,4.62,;-.67,4.62,;-2,5.39,;-3.33,4.62,;-.67,3.08,;-2,2.31,;-2,.77,;-3.33,,;-3.33,-1.54,;-2,-2.31,;-.67,-1.54,;-.67,,;.67,.77,;2,,;.67,2.31,;2,3.08,;-2,-3.85,;-3.33,-4.62,;-3.33,-6.16,;-2,-6.93,;-2,-8.47,;-.67,-9.24,;.67,-8.47,;.67,-6.93,;2,-6.16,;2,-4.62,;3.33,-6.93,;3.33,-8.47,;-.67,-6.16,;-.67,-4.62,)| Show InChI InChI=1S/C28H23Cl2N3O5/c1-5-24(34)33-8-9-38-21-7-6-15(11-20(21)33)18-12-19-16(14-31-18)10-17(28(35)32(19)2)25-26(29)22(36-3)13-23(37-4)27(25)30/h5-7,10-14H,1,8-9H2,2-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...				US Patent US9695165 (2017) BindingDB Entry DOI: 10.7270/Q25M67QZ
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