Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM103870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM103870 (US9695165, 53) Show SMILES CCn1c2cc(ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O)-c1cc2N(C(C)COc2cc1F)C(=O)C=C |(3.33,.77,;2,,;.67,.77,;-.67,,;-.67,-1.54,;-2,-2.31,;-3.33,-1.54,;-3.33,,;-2,.77,;-2,2.31,;-.67,3.08,;-.67,4.62,;-2,5.39,;-3.33,4.62,;-2,6.93,;-3.33,7.7,;-4.67,6.93,;-.67,7.7,;.67,6.93,;2,7.7,;2,9.24,;.67,5.39,;2,4.62,;.67,2.31,;2,3.08,;-2,-3.85,;-.67,-4.62,;-.67,-6.16,;.67,-6.93,;.67,-8.47,;2,-9.24,;-.67,-9.24,;-2,-8.47,;-2,-6.93,;-3.33,-6.16,;-3.33,-4.62,;-4.67,-3.85,;2,-6.16,;2,-4.62,;3.33,-6.93,;4.67,-6.16,)| Show InChI InChI=1S/C30H26Cl2FN3O5/c1-6-26(37)36-15(3)14-41-23-10-19(33)17(9-22(23)36)20-11-21-16(13-34-20)8-18(30(38)35(21)7-2)27-28(31)24(39-4)12-25(40-5)29(27)32/h6,8-13,15H,1,7,14H2,2-5H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...				US Patent US9695165 (2017) BindingDB Entry DOI: 10.7270/Q25M67QZ
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