Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM209303'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM209303 (US9266883, 61) Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM209303 (US9266883, 61) Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM209303 (US9266883, 61) Show SMILES COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N Show InChI InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as reduction in cell viability incubated for 2 days by cell proliferation assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair