Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre... | US Patent US11001572 (2021) BindingDB Entry DOI: 10.7270/Q2Z322RS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent | Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi... | US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT | |||||||||||
More data for this Ligand-Target Pair |