Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM50465120'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50465120 (CHEMBL4279848) Show SMILES COCCNc1cc(NC(=O)N(CCOC)c2cccc(C=O)n2)ncc1C#N Show InChI InChI=1S/C19H22N6O4/c1-28-8-6-21-16-10-17(22-12-14(16)11-20)24-19(27)25(7-9-29-2)18-5-3-4-15(13-26)23-18/h3-5,10,12-13H,6-9H2,1-2H3,(H2,21,22,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of FGFR4 (388 to 802 residues) (unknown origin) using 5-Fluo-Ahx-KKKKEEIYFFFG-NH2 as substrate after 60 mins by microfluidic mobility shif...				ACS Med Chem Lett 9: 215-220 (2018) Article DOI: 10.1021/acsmedchemlett.7b00485 BindingDB Entry DOI: 10.7270/Q27947C7
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50465120 (CHEMBL4279848) Show SMILES COCCNc1cc(NC(=O)N(CCOC)c2cccc(C=O)n2)ncc1C#N Show InChI InChI=1S/C19H22N6O4/c1-28-8-6-21-16-10-17(22-12-14(16)11-20)24-19(27)25(7-9-29-2)18-5-3-4-15(13-26)23-18/h3-5,10,12-13H,6-9H2,1-2H3,(H2,21,22,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM50465120 (CHEMBL4279848) Show SMILES COCCNc1cc(NC(=O)N(CCOC)c2cccc(C=O)n2)ncc1C#N Show InChI InChI=1S/C19H22N6O4/c1-28-8-6-21-16-10-17(22-12-14(16)11-20)24-19(27)25(7-9-29-2)18-5-3-4-15(13-26)23-18/h3-5,10,12-13H,6-9H2,1-2H3,(H2,21,22,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50465120 (CHEMBL4279848) Show SMILES COCCNc1cc(NC(=O)N(CCOC)c2cccc(C=O)n2)ncc1C#N Show InChI InChI=1S/C19H22N6O4/c1-28-8-6-21-16-10-17(22-12-14(16)11-20)24-19(27)25(7-9-29-2)18-5-3-4-15(13-26)23-18/h3-5,10,12-13H,6-9H2,1-2H3,(H2,21,22,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of TEL-fused FGFR4 cytoplasmic/juxta membrane domain (unknown origin) expressed in mouse Ba/F3 cells assessed as reduction in FGFR4 autoph...				ACS Med Chem Lett 9: 215-220 (2018) Article DOI: 10.1021/acsmedchemlett.7b00485 BindingDB Entry DOI: 10.7270/Q27947C7
					More data for this Ligand-Target Pair