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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM50554188'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 4


(Homo sapiens (Human))
BDBM50554188
PNG
(CHEMBL4744686)
Show SMILES COc1cc(OC)c(Cl)c(Nc2ncccc2-c2cc(Nc3c(C)cccc3NC(=O)C=C)ncn2)c1Cl
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal 6x-His tagged FGFR4 catalytic domain (445-753 residues) (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incuba...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00044
BindingDB Entry DOI: 10.7270/Q24Q7ZNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Fibroblast growth factor receptor 4


(Homo sapiens (Human))
BDBM50554188
PNG
(CHEMBL4744686)
Show SMILES COc1cc(OC)c(Cl)c(Nc2ncccc2-c2cc(Nc3c(C)cccc3NC(=O)C=C)ncn2)c1Cl
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 2.93E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal 6x-His tagged FGFR4 C552A mutant (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incubated for 30 mins by scin...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00044
BindingDB Entry DOI: 10.7270/Q24Q7ZNV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)