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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50438035'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50438035
PNG
(CHEMBL2409603)
Show SMILES COc1cc(Nc2nc(C)nc(Nc3ccccc3NC(=O)N(C)C)n2)cc(OC)c1OC
Show InChI InChI=1S/C22H27N7O4/c1-13-23-20(25-14-11-17(31-4)19(33-6)18(12-14)32-5)28-21(24-13)26-15-9-7-8-10-16(15)27-22(30)29(2)3/h7-12H,1-6H3,(H,27,30)(H2,23,24,25,26,28)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.43E+4n/an/an/an/an/an/a



Universit£ Paris Descartes

Curated by ChEMBL


Assay Description
Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...

Bioorg Med Chem Lett 23: 4552-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.038
BindingDB Entry DOI: 10.7270/Q2GM88RC
More data for this
Ligand-Target Pair